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Hypervirulent Klebsiella pneumoniae studied in the US

February 22nd, 2012

Hypervirulent strains of Klebsiella pneumoniae identified in the US have the potential to become the next 'superbug', according to researchers from University at Buffalo.

Traditional strains of Klebsiella pneumoniae have largely affected hospitalised populations, who have weaker defence systems. Read the rest of this entry »

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Malaria drug and chemotherapy combination ‘boosts cancer treatment’

February 22nd, 2012

Cancer CellA new combination of chemotherapy and a drug commonly used to treat malaria and rheumatoid arthritis holds the potential to boost the power of cancer treatments.

Ravi K Amaravadi, MD, an assistant professor of medicine at the Perelman School of Medicine, is among the scientists looking at the potential of combining hydroxychloroquine (HCQ) with cancer treatments including chemotherapy, targeted therapy, radiation, and immunotherapy. Read the rest of this entry »

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Liver diseases and obesity ‘could be caused by defects in protein’

February 20th, 2012

Scientists have found that a defect in a protein acting as a dietary fat sensor could cause obesity and liver disease.

A study carried out by experts in France, the UK and Japan, led by Professor Philippe Froguel from the School of Public Health at Imperial College London, showed that there is now a promising target for new drugs, which could help to target the health problems. Read the rest of this entry »

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Aggressive bowel cancers could be targeted by “previously unappreciated” protein

February 20th, 2012

US researchers from the Massachusetts General Hospital Cancer Center have found that by targeting a "previously unappreciated" protein, they could discover a new way to treat aggressive bowel cancers.

The findings were published in the journal Cell, and they showed that the TAK1 protein was key to the growth of KRAS-dependant cancer cells. Read the rest of this entry »

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Experts create living 3D model of brain tumour

February 20th, 2012

A living 3D model of a brain tumour has been created by scientists, which is being used to look at the effectiveness of therapeutics on this form of cancer.

Experts from Brown University managed to create a glioma with a network of blood vessels surrounding it. Read the rest of this entry »

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